Embryonic Pathway Delivers Stem Cell Traits

Thursday, May 15, 2008 - 11:35 in Biology & Nature

Cells that undergo an epithelial-to-mesenchymal transition (EMT) show properties of stem cells, including the ability to self-renew. In addition, stem cells exhibit properties of cells that undergo EMT. Strikingly, both normal and cancer stem cells can be generated from differentiated cells by EMT. Understanding the role of EMT in adult stem cell creation may lead toward the development of healthy stem cells for regenerative medicine and provide drug targets for cancer.

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