Researchers identify promising cancer drug target in prostate tumors

Tuesday, July 1, 2008 - 16:35 in Health & Medicine

Scientists at Dana-Farber Cancer Institute report they have blocked the development of prostate tumors in cancer-prone mice by knocking out a molecular unit they describe as a "powerhouse" that drives runaway cell growth.In a letter appearing in an advanced online publication by the journal Nature, the researchers said the growth-stimulating molecule called p110beta — part of a cellular signaling network disrupted in several common cancers — is a promising target for novel cancer therapies designed to shut it down. The report's lead authors are Shidong Jia, Zhenning Liu, Sen Zhang, and Pixu more

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