Rockefeller scientists pioneer new methodology to determine mechanisms of drug action

Thursday, May 24, 2012 - 12:20 in Biology & Nature

Researchers led by Tarun Kapoor at The Rockefeller University in collaboration with Olivier Elemento at Weill Cornell Medical College have hit on a new method for determining a drug’s molecular target that takes the guesswork out of the equation. The approach makes use of RNA sequencing and advances in data processing technologies to examine all of the differences between a drug-resistant cell and a normal cell and pinpoint the change most likely to cause resistance, which may suggest the drug’s target. More »

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