High fat diet increases inflammation in the mouse colon

Wednesday, November 11, 2009 - 17:28 in Biology & Nature

In mice fed a diet high in fat and low in fiber, vitamin D and calcium — the so-called Western diet — expression of a series of genes collectively associated with immune and inflammatory responses was altered. The findings show that a Western diet induces oxidative stress and alters immune responses in the colon of mice long before tumors occur.

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