Discovery could help scientists stop the “death cascade” of neurons after a stroke

Millions of stroke victims suffer permanent brain damage every year because neurons start spitting out the neurotransmitter glutamate when they are deprived of oxygen. It doesn’t take long before the brain cells drown in their own salts. Now a team of scientists at Rockefeller University have for the first time found a way to slow cell death by blocking a specific subunit of the glutamate receptor, a method that avoids the devastating side effects of disrupting the receptor as a whole.

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