'A lion of nephrology' noted for unravelling the chemistry of the rare Dent's diseaseOliver Wrong, who has died aged 87, was a distinguished professor of medicine who will be remembered for unravelling the chemistry of Dent's disease, a kidney condition which he self-effacingly named after his late colleague and mentor, Charlie Dent. Dent had recognised the condition 30 years earlier, but it was Wrong's work that really threw light on it.The disease is rare and is carried by females but affects males. Patients suffer rickets, kidney stones and renal failure because they excrete excessive amounts of calcium and protein from their kidneys. Even with the best care, Dent's syndrome leads to death in middle age. Thanks to Wrong, patients are offered supportive care, which prolongs life and improves its quality. Wrong also contributed to the understanding of another inherited disease, kidney-produced acidosis, now recognised as widespread in the tropics.Wrong was...
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