Nanoparticles could damage DNA at a distance

Friday, November 6, 2009 - 03:56 in Biology & Nature

Lab tests show that metal nanoparticles can affect DNA without actually coming into contact with it – though the results are difficult to extrapolate to the human bodyNanoparticles of metal can damage the DNA inside cells even if there is no direct contact between them, scientists have found. The discovery provides an insight into how the particles might exert their influence inside the body and points to possible new ways to deliver medical treatments.The preliminary work also raises questions about the safety of nanoparticles – which are a thousand times smaller than the width of a human hair and used in everything from sunscreens to electronics – though the researchers point out that the doses they used in their study were higher than anything a person might come into contact with.They also said it was difficult to extrapolate results from their laboratory tests to the human body.In the experiment, scientists...

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