RNA Is New Target For Anticancer Drugs

Sunday, April 19, 2015 - 22:20 in Biology & Nature

Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery unveils a whole new set of potential targets: the RNA intermediaries between DNA and proteins. This RNA, called messenger RNA, is a blueprint for making proteins. Messenger RNA is created in the nucleus and shuttled out into the cell cytoplasm to hook up with protein-making machinery, the ribosome. Most scientists have assumed that these mRNA molecules are, aside from their unique sequences, generic, with few distinguishing characteristics that could serve as an Achilles heel for targeted drugs. read more

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