SUMO Can Keep Gene Expression In Check

Living beings can keep gene expression in check, which might partly explain the uncontrolled gene expression found in many cancers, according to a new paper/"Using yeast as a model organism, we studied the Tup1 protein, a negative regulator of gene expression," says Biology Professor Emanuel Rosonina. "This protein binds to some genes and blocks their expression, helping to ensure genes that shouldn't be turned on remain inactive."  read more

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