Mammalian Heart Regenerative Capacity Depends On Severity Of Injury
Monday, January 26, 2015 - 12:50
in Health & Medicine
A new study by researchers at Children's Hospital Los Angeles has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using cryoinjury - damaging the heart through exposure to extreme cold in order to mimic cellular injury caused by myocardial infarction - investigators found that neonatal mouse hearts can fully recover normal function following a mild injury, though fail to regenerate after a severe injury. Published online by the journal Developmental Biology, the study suggests that cardiac regeneration strategies should be based on the type and severity of heart injury. read more