So How Do Drugs Work?

All right to start this post I have to warn everyone that there is going to be a little math at the start, but not much, only one easy equation that you need to have a sense of if you are going to understand what drugs that inhibit enzymes do.  This equation is universal and can be easily expanded to describe most molecular interactions.  Actually the most basic form of it is the IC50 equation which has been used as a crutch for describing drug interactions for years.  So if nothing else you might get a sense of what researchers are referring to when they get excited about IC50 values.  read more

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