Antibiotics Of The Future
Sunday, October 19, 2014 - 12:01
in Health & Medicine
Computer simulations show how bacteria are able to destroy antibiotics, focusing on the role of enzymes in the bacteria which split the structure of the antibiotic and stop it working, making the bacteria resistant. The new findings show that it's possible to test how enzymes react to certain antibiotics and thus design new antibiotics with a much lower risk of resistance, and even to choose the best medicines for specific outbreaks. Using QM/MM - quantum mechanics/molecular mechanics simulations – the research team were able to gain a molecular-level insight into how enzymes called 'beta-lactamases' react to antibiotics. read more