Sharks Won't Lead To Better Cancer Treatment - But A Hippo Might

Thursday, July 11, 2013 - 21:00 in Health & Medicine

A potential new pathway to treat cancer is actually called the Hippo pathway - and it's a key control in how our organs are perfectly suited to our bodies, despite differences in size.  Using mice genetically lacking an enzyme called Set7, the results show that methylation of a protein called Yap is critical for the function of the Hippo pathway. Loss of the Set7 enzyme resulted in cell growth and larger organs.   read more

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