Shortened Clinical Trials Exaggerate Treatment Effects

Clinical trials ended early due to positive treatment effects likely exaggerate those effects, according to a new review published in JAMA. The authors caution that researchers should resist pressures to end clinical trials early because of the potential risk to patients in the trials. The clinical trials reviewed were ended early because of a convincing -- and usually large -- apparent difference between an experimental treatment and an existing standard therapy. The studies were ended so participants taking a placebo or less effective medications could also take the studied drug. read more

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