Cocaine Regulates Gene Expression - And Has Long-Lasting Impact On Behavior

Wednesday, May 13, 2009 - 14:14 in Psychology & Sociology

New research sheds light on how cocaine regulates gene expression in a crucial reward region of the brain to elicit long-lasting changes in behavior. The study in Neuron provides insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction. It is well established that addictive drugs induce persistent changes in the brain's reward circuits. Previous research has indicated that addiction to drugs such as cocaine is associated with altered gene expression in the nucleus accumbens (NAc), a region of the brain that is involved in motivation, pleasure, and reward. read more

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