Diminuendo - Mouse Model Rats Out MicroRNA In Hearing Loss

Monday, April 27, 2009 - 15:56 in Biology & Nature

Scientists of Helmholtz Zentrum München, led by Professor Martin Hrabé de Angelis, director of the Institute of Experimental Genetics, have developed a new mouse model with a genetic mutant in which a single base of a specific microRNA seed region has been altered. Mice carrying this miR-96 mutation suffer progressive hearing loss as they get older.    Moreover, if they carry two of these mutants, their sensory hair cells are impaired from birth on. read more

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