A Genetic Variation For Teen Tobacco Addiction?
Common genetic variations affecting nicotine receptors in the nervous system can significantly increase the chance that European Americans who begin smoking by age 17 will struggle with lifelong nicotine addiction, according to researchers at the University of Utah and their colleagues at University of Wisconsin-Madison. The study highlights the importance of public health efforts to reduce the number of youth who begin smoking. These common gene variations - single nucleotide polymorphisms (SNPs) - are changes in a single unit of DNA. SNPs that are linked and inherited together are called a haplotype. The researchers found that one haplotype for the nicotine receptor put European American smokers at greater risk of heavy nicotine dependence as adults, but only if they began daily smoking before the age of 17. A second haplotype actually reduced the risk of adult heavy nicotine dependence for people who began smoking in their youth. Read More...
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