Nanoparticles deliver 'suicide gene' therapy to pediatric brain tumors growing in mice

Wednesday, January 8, 2020 - 14:40 in Health & Medicine

Researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a ''suicide gene'' to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals' survival.

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