How a major tumor suppressor pathway becomes deactivated
Thursday, April 4, 2019 - 12:10
in Health & Medicine
The Hippo pathway is an important biological tumor suppressor program that controls cell growth and organ size in humans. Cancer cells have been found to frequently deactivate Hippo signaling in order to achieve increased cell growth and become more aggressive. However, how the Hippo pathway becomes deregulated in human cancers is still poorly understood.