Androgen receptor, treatment target for prostate cancer, imports into mitochondria
Tuesday, March 19, 2019 - 11:50
in Health & Medicine
Androgens stimulate prostate cancer cells to grow. Many drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor, or AR. Researchers have discovered a new function of the AR in prostate cells -- the AR is imported into and localizes to mitochondria of the cell, where it plays a novel role in regulating multiple mitochondrial processes.