Noninvasive light-sensitive recombinase for deep brain genetic manipulation

Tuesday, January 22, 2019 - 16:10 in Paleontology & Archaeology

A research team presents a noninvasive light-sensitive photoactivatable recombinase suitable for genetic manipulation in vivo. The highly light-sensitive property of photoactivatable Flp recombinase will be ideal for controlling genetic manipulation in deep mouse brain regions by illumination with a noninvasive light-emitting diode. This easy-to-use optogenetic module will provide a side-effect free and expandable genetic manipulation tool for neuroscience research.

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