Scientists map sex chromosome evolution in pathogenic fungi

Friday, August 11, 2017 - 21:02 in Biology & Nature

Researchers recently mapped the evolutionary turning point that transformed the pathogenic Cryptococcus fungus from an organism with thousands of sexes to only two. They found that during evolution, a reshuffling of DNA known as translocation brought together separate chunks of sex-determining genes onto a single chromosome, essentially mimicking the human X or Y chromosome. Surprisingly, these translocations occurred at the chromosome's centromeres, regions so dense that they were once thought to suppress recombination.

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