Researchers use a single molecule to command stem cells to build new bone

An easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue has been identified by researchers: feed them adenosine, a naturally occurring molecule in the body. The stem-cell-derived bone tissue helped repair cranial bone defects in mice without developing tumors or causing infection. The work could lead to regenerative treatments for patients with critical bone defects and soldiers who have suffered traumatic bone injuries.

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