Mutant enzyme study aids in understanding of sirtuin's functions
Tuesday, June 28, 2016 - 14:11
in Biology & Nature
The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood. A team of researchers has devised a method for isolating one specific enzyme activity to determine its contribution and lead to better overall understanding of SIRT6.