Out of tune: Mismatch of vascular, neural responses suggests limits of fMRI

Wednesday, May 25, 2016 - 13:51 in Biology & Nature

During sensory stimulation, increases in blood flow are not precisely 'tuned' to local neural activity, report investigators. This finding challenges the long-held view that vascular and local neural responses are tightly coupled and could suggest limitations for functional magnetic resonance imaging, which assumes that vascular changes reflect a proportional change in local neural activity.

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