Genetic variations that boost PKC enzyme contribute to Alzheimer's disease
Tuesday, May 10, 2016 - 15:10
in Biology & Nature
In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons. Now, researchers have found that the enzyme Protein Kinase C (PKC) alpha is necessary for amyloid beta to damage neuronal connections. They also identified genetic variations that enhance PKC alpha activity in patients with Alzheimer's disease.