Chromosomes reconfigure as cell division ends
Sunday, February 7, 2016 - 12:21
in Biology & Nature
Cells reach a state called senescence when they stop dividing in response to DNA damage. This change can matter greatly to health, but scientists do not yet have a clear picture of how this change impacts the genome. A new study shows that a cell's chromosomes become physically reconfigured at senescence, leading to significant differences in what genes are expressed.