Gut microorganisms cause gluten-induced pathology in mouse model of celiac disease

Thursday, October 8, 2015 - 08:50 in Biology & Nature

Investigators interested in celiac disease have wondered why only 2 to 5 percent of genetically susceptible individuals develop the disease. Attention has focused on whether environmental determinants, including gut microorganisms, contribute to the development of celiac disease. Using a humanized mouse model of gluten sensitivity, a new study has found that the gut microbiome can play an important role in the body's response to gluten.

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