Possible therapeutic target for common, but mysterious brain blood vessel disorder
Monday, January 26, 2015 - 15:30
in Health & Medicine
Tens of millions of people worldwide have abnormal, leak-prone sproutings of blood vessels in the brain called cerebral cavernous malformations. These abnormal growths can lead to seizures, strokes, and hemorrhages, yet their precise molecular cause has never been determined. Now, cardiovascular scientists have studied this pathway in heart development to discover an important set of molecular signals, triggered by CCM-linked gene defects, that potentially could be targeted to treat the disorder.