Model explains why HIV prevention dosing differs by sex
Friday, October 31, 2014 - 04:03
in Health & Medicine
A mathematical model predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection via anal sex. This finding helps explain why two large clinical trials testing HIV pre-exposure prophylaxis, or PrEP, in women failed to show efficacy.