'Achilles heel' in metabolic pathway identified, could lead to new treatments for lung cancer
Wednesday, October 8, 2014 - 11:01
in Health & Medicine
An “Achilles heel” in a metabolic pathway crucial to stopping the growth of lung cancer cells has been identified by researchers. At the heart of this pathway lies PPAR³, a protein that regulates glucose and lipid metabolism in normal cells. Researchers demonstrated that by activating PPAR³ with antidiabetic drugs in lung cancer cells, they could stop these tumor cells from dividing.