Brain inflammation dramatically disrupts memory retrieval networks, study finds

Brain inflammation can rapidly disrupt our ability to retrieve complex memories of similar but distinct experiences, according to scientists. The study specifically identifies how immune system signaling molecules, called cytokines, impair communication among neurons in the hippocampus, an area of the brain critical for discrimination memory. The findings offer insight into why cognitive deficits occurs in people undergoing chemotherapy and those with autoimmune or neurodegenerative diseases.

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