Early lineage segregation during early mammalian heart development defined by researchers
Monday, August 25, 2014 - 15:31
in Biology & Nature
During embryonic development, the cells that will form the heart need to be specified at the correct time, migrate at the correct place, proliferate to ensure the harmonious morphogenesis and growth of the heart. Any defects during this critical stage of development will lead to congenital heart diseases. While different progenitors that contribute to the development of the heart have been identified, it remains unclear whether these cells arise from common progenitors or derive from distinct progenitors that are specified at different time during development.