Two-lock box delivers cancer therapy: Nano-delivery system targets cancer cells

A tunable virus that works like a safe deposit box has been developed by scientists. It takes two keys to open it and release its therapy for cancer and other diseases. The adeno-associated virus (AAV) developed by bioengineers unlocks only in the presence of two selected proteases, enzymes that cut up other proteins for disposal. Because certain proteases are elevated at tumor sites, the viruses can be designed to target and destroy the cancer cells.

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