Loss of anti-aging gene possible culprit in age-related macular degeneration

The loss of an anti-aging gene induces retinal degeneration in mice and might contribute to age-related macular degeneration, the major cause of blindness in the elderly. Researchers say that in their animal studies, loss of expression of the aging-suppressor gene Klotho leads to characteristics observed in wet and dry macular degeneration seen in humans. Researchers say gene therapy or cell therapy might be able to induce new expression of Klotho in the aging retina.

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