Zinc fingers: A new tool in the fight against Huntington's disease

Wednesday, October 10, 2012 - 21:00 in Biology & Nature

Huntington's disease (HD) is an inherited genetic disorder caused by the multiple repetition of a DNA sequence (the nucleotides CAG) in the gene encoding a protein called "Huntingtin". People who do not suffer from the disease have this sequence repeated 10 to 29 times. But in an affected person, the triplet is present more than 35 times. New research provides positive results reducing the chromosomal expression of the mutant gene, which would prevent the development of disease.

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