Chaperone protein subverts removal of glaucoma-causing protein

Tuesday, October 9, 2012 - 13:01 in Biology & Nature

The chaperone protein Grp94 can interfere with the clearance of another protein known to cause the glaucoma when mutated, a new study has found. The researchers also demonstrated that a new specific inhibitor of Grp94 facilitates clearance of the genetically-defective protein, called myocilin, from cells.

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