What light through yonder tiny window breaks? Researchers optimize photoluminescent probes to study dna and more

Sorting good data from bad is critical when analyzing microscopic structures like cells and their contents, according to researchers. The trick is to find the right window of time through which to look. A new paper offers a methodology to optimize the sensitivity of photoluminescent probes using time-resolved spectroscopy. Researchers found their technique gave results nearly twice as good as standard fluorescence spectroscopy does when they probed for specific DNA sequences.

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