Expression of pluripotency-associated gene marks many types of adult stem cells

Thursday, October 6, 2011 - 15:30 in Biology & Nature

Investigators have found that Sox2 -- one of the transcription factors used in the conversion of adult stem cells into induced pluripotent stem cells -- is expressed in many adult tissues where it had not been previously observed and that Sox2-expressing cells in those tissues are true adult stem cells that can give rise to all mature cell types in those tissues.

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