First recurrent gene fusion identified in ovarian cancer

Researchers studying ovarian cancer have discovered that, in a substantial fraction of ovarian tumors, a gene closely related to the estrogen receptor is broken and fused to an adjacent gene by a chromosome rearrangement -- a finding that could shed light on how these deadly tumors develop and spread. Identifying a gene fusion in ovarian cancer may provide scientists with a new opportunity to identify ovarian cancers early in their development and perhaps develop new treatments.

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