Targeting innate immunity in malaria: Novel DNA sensing pathway linked to increased susceptibility to malaria
Thursday, August 4, 2011 - 22:30
in Health & Medicine
Scientists have uncovered a novel DNA-sensing pathway important to the triggering of an innate immune response for malaria. Activation of this pathway appears to stimulate production of an overabundance of type-1 interferon by the immune system that may contribute to inflammation and fever in malaria patients and could play a part in susceptibility for the most common and lethal form of malaria known as plasmodium falciparum.