Atomic structure discovered for a sodium channel that generates electrical signals in living cells

Wednesday, July 13, 2011 - 14:30 in Biology & Nature

Scientists have determined the atomic structure of a sodium channel, a pore in membranes of excitable cells, such as brain or heart cells, that emit electrical signals. They gate charged particles crossing the cell membrane to generate electrical currents. These encode information in the brain and make heart muscle contract. Many medications and neurotoxins act on sodium channels. Never before have researchers obtained a high resolution crystal structure of all atoms of this complex protein molecule and their three dimensional relationships.

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