Genetics of melanoma chemoresistance
Sunday, June 5, 2011 - 19:30
in Biology & Nature
Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, researchers reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") that can ultimately promote metastasis and contribute to melanoma relapse.