Digital versus analog control over cortical inhibition in the brain

In the cerebral cortex, the balance between excitation and inhibition is thought to be mediated by the primary mode of neuronal communication: "all-or-none" action potentials, or spikes. However, researchers in China have discovered a new strategy by which the cortex can maintain this balance, by showing that the amount of inhibition depends on the membrane potentials in pyramidal cells, which represents an "analog" strategy.

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