Key mutations act cooperatively to fuel aggressive brain tumor

Monday, March 14, 2011 - 16:31 in Health & Medicine

Mutations in three pathways important for suppressing tumors cooperate to launch glioblastoma, an aggressive brain tumor that strikes children and adults. But new research shows those changes alone are not sufficient to cause cancer. Tumor formation requires additional mutations, some affecting different points in the same disrupted regulatory pathways.

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