Insulin-like signal needed to keep stem cells alive in adult brain

Most parts of the fruit fly brain, as well as the human brain, are devoid of neural stem cells, which means that once a nerve cell dies, it can't be replaced. A new study in fruit flies shows one way to keep stem cells from dying as the brain matures. Whereas stem cells blocked from apoptosis persist, they suffer insulin withdrawal; revving up the insulin system gives healthy stem cells and generates normal-looking neurons.

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