African pygmy mice: Females are XY ... researchers find out why

Wednesday, February 24, 2010 - 23:14 in Biology & Nature

In a great majority of cases, the Y chromosome determines sex in mammals. The African pygmy mouse M. minutoides is an exception to this rule. In this species, which is a close relative of the house mouse, it is the X chromosome that determines sex. Researchers in France have just identified this unexpected case of sex determination. These scientists have demonstrated a particular chromosomal rearrangement on the X chromosome of this mouse. This work should provide a clearer understanding of how classic sex determination functions in mammals.

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