Progesterone for traumatic brain injury tested in phase III clinical trial

Researchers at 17 medical centers soon will begin using the hormone progesterone to treat patients who experience traumatic brain injury (TBI). The treatment is part of an NIH-funded, randomized, double-blind Phase III clinical trial that will enroll approximately 1,140 people beginning in March, 2010. An earlier trial in 100 patients found that giving progesterone to trauma victims shortly after a brain injury appears to be safe and may reduce the risk of death and long-term disability.

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