Scientists find donut-shaped structure of enzyme involved in energy metabolism
Thursday, February 18, 2010 - 00:21
in Biology & Nature
Using advanced X-radiation techniques, researchers were able to visualize one of these terminals inside of an enzyme that degrades proline, which is an amino acid that has a central role in metabolism. In humans, proline is important for suppression of cancer, cell death and oxidation. Understanding the structure of this enzyme will help scientists better understand how it functions and develop drugs that may inhibit its catalytic function.