Bacterial protein mimics its host to disable a key enzyme

Friday, January 1, 2010 - 22:14 in Biology & Nature

Helicobacter pylori infects up to 90 percent of people in the developing world and causes gastric ulcers and cancers of the gut. Now scientists have revealed a subterfuge used by the bacterium to trick stomach cells into playing along. By injecting a protein into the stomach lining that mimics a native protein but has its opposite effect, the bacterium shuts down a process that helps properly structure stomach tissue, scientists say.

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